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42 Considering the current widespread use of APAP alone and in opiate combinations among adults of advanced age (to treat cancer pain or chronic musculoskeletal pains), one must not forget to monitor patients for complications of long-term and high-dose APAP use

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177 A larger study involving 90 HIV-positive patients with antiretroviral toxic neuropathy found that taking 500 mg of ALC intramuscularly twice per day for 14 days resulted in statistically significant improvements in weekly mean pain ratings versus placebo