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Notably, oxidative protein modifications are not readily reversible, unlike reversible thiol oxidation, which underscores their diagnostic significance (87)

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In detail, the last seven amino acids of the Gα s -α5 helix connect with R139 3.50 , A142 3.53 , and I143 3.54 of TM3, L236 5.65 of TM5, K308 6.30 , A307 6.29 and R310 6.32 of TM6, and N374 8.47 at the TM7–Helix8 hinge in CCK1R (Fig