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ketorolac is contraindicated for use in patients with aspirin-sensitive asthma or the aspirin triad because of the approximate 5% cross-sensitivity that occurs between aspirin and NSAIDs

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8 weeks post completion of final study therapy (whether blinded or open label /unblinded), study subjects will be reviewed for a final time for follow up on their clinical progress, assessment of disease activity and collection of final blood and faecal samples for study analysis