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Effects of SAG on Histopathological Alterations and Liver Function Induced by CCl4 Chronic Exposure In liver, CCl4 administration increased the myeloperoxidase (MPO) activity, which is used as an indicator of polymorphonuclear (PMN) cell infiltration (Figure 8F), liver cell damage and necrosis (Figure 8C,E), whereas the sham (Figure 8B,E) and sham + SAG (Figure 8A,E) groups showed normal histological architecture