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Although HQ can function as an alternative substrate for TYR, the subsequent enzymatic reaction results in the production of reactive oxygen species (ROS), which is thought to be responsible for its skin-lightening properties, with possible associated side effects including leukoderma and exogenous ochronosis (82,83)

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Changes in fatty acids including elongation, desaturation, β-oxidation, peroxidation, and incorporation into phospo- and complex lipids can play an essential role in their metabolic function