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For 14 days, Wistar rats given oral ethanol extract 50–100 mg/kg body weight showed better haematologic parameters, elevated antioxidant gene activity, and altered sickle-cell-related gene expression without causing appreciable harm (Ameh & Alafi, n.d.)

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By observing mammary gland composition and architecture after TTM treatment, this study illustrated that TTM induced breast hypoplastic remodeling by weakening the epithelial duct branch system and reducing breast microvascular density, ultimately impeding breast tumor growth [115]