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Their results showed an improvement in mortality and liver functional tests (serum transaminases, lactate dehydrogenase, and international normalized ratio) in the NAC group starting 24 h after the therapy commenced and lasting for the duration of the two-week follow-up

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A phase I clinical trial (NCT01491893) demonstrated that intratumoral infusion of PVSRIPO in recurrent GBM patients was tolerated and produced increased mOS (12.5 vs

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