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In addition, light also triggers ROS and Fe 2+ burst, lipid peroxidation, and decreased cell viability of RPE cell lines, resulting in retinal damage and degeneration by inducing ferroptosis via GSH-GPX4 and AIFM2-CoQ10-NADH systems ( 2.3 Glaucoma RGC is located in the innermost layer of the retina, composed of multipolar ganglion cells, and its dendrites are mainly connected to bipolar cells (Masland, 2012)
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