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We propose here that the premature and accelerated aging of HIV-patients can also be caused by adverse effects of antiretroviral drugs, specifically those that affect the mitochondria

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Similar to the findings in patients with AD, the expression levels of APP-Kla were significantly decreased in the hippocampus and cortex tissues of 6-month-old APP23/PS45 double-transgenic AD model mice compared with age-matched WT mice (Figure 1, E–H)