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Its cytotoxic mode of action is mediated by its interaction with DNA to form DNA adducts, primarily intrastrand crosslink adducts, which activate several signal transduction pathways, including those involving ATR, p53, p73, and MAPK, and culminate in the activation of apoptosis

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Sensory issues: Brain injuries typically include sensory problems like blurred vision, sensitivity to light or sound, ringing in the ears or an inability to smell normally