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Symptoms mainly encompass sensation of throat closure, upper airway swelling, nausea-vomiting, tachycardia, difficulty breathing without wheezing or stridor, angioedema, hypotension, and dry cough ( Capillary leak syndrome Capillary leak syndrome (CLS) is the leakage of fluids in the vessels into the extravascular space

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Sterile water contains no preservative and must be discarded after a single use