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Liver Protection and Detoxification In cases of acetaminophen overdose or other toxic insults, NAC restores depleted glutathione, enabling the neutralization of harmful metabolites, such as NAPQI, thus preventing liver cell damage

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Some studies in mouse hyperlipidemia models have shown that the NLRP3 inflammasome can cause AS, but it may require a second insult, such as oxidized mitochondrial DNA accumulation or impaired cholesterol efflux, which may cause serious systemic inflammatory (68)