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Similar content being viewed by others Introduction Excessive alcohol intake and high-calorie food consumption are two major etiological factors in the pathogeneses of chronic liver diseases worldwide, causing alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), respectively

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In practice, co-administration with antiplatelet agents or warfarin warrants caution, and theoretical DOAC interactions remain a concern given curcumin’s inhibition of P-glycoprotein and reported modulation of CYP3A4, pathways central to apixaban/rivaroxaban disposition [167,168]