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A drought was in full swing when Father Manuel de Aguirre stated that there was “plenty of land for everyone, but not enough water to sustain the existing Spanish and Indian population.”[44] Conversely, the early 1800s were moist, and sufficient water flowed down the Santa Cruz to support impressive levels of agricultural production

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The formation of both a mono- and a bis-substituted glutathione conjugate of hexachlorobutadiene by isolated rat hepatocytes and following in vivo administration to the rat