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In the THRIVE-AA1/AA2 clinical trials of deuruxolitinib, Hebert highlighted how patients continued to improve “well past the primary endpoint of 24 weeks.” Overall, 48.8% and 76.6% of patients achieved a Severity of Alopecia Tool (SALT) score ≤20 by Week 68 of treatment with deuruxolitinib assessed by last observation carried forward and as observed, respectively (Figure 1)

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Intracellular GlcNAcylation of serine and threonine residues is a well-known and widely investigated post-translational modification in plant cells