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The p K a of Cys A of strep-MBP-GRXC2 was between 3.0 and 3.5 in the wild-type protein and between 3.5 and 4.0 in the strep-MBP-GRXC2-CSS variant (Fig

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Comment: Several commenters did not support the proposed inclusion of MIPS Q220: Functional Status Change for Patients with Low Back Impairments in the ASM low back pain quality measure set, noting concerns that while Focus on Therapeutic Outcomes, Inc (FOTO) permits free access to components of the measure, the website's functionality is not interoperable with clinicians' chosen health IT systems and leading to a disjointed and labor intensive manual process, requiring the licensed FOTO's tools to report measure data and increasing reporting burden and costs for both clinicians and vendors