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Size:39N
In addition to NO, which is an important protective factor in the vasculature and a neurotransmitter in the nervous system,21 oxygen radicals are, for example, essential in the immune defence, as well as in the regulation of cellular growth and gene expression.22 But too much of a good thing can literally be harmful, because radicals are also highly dangerous by-products of the cellular metabolism.23 An oxidative imbalance, i.e., a disturbance in the balance between the production of ROS (especially free radicals) and antioxidant defenses, has been described as an oxidative stress status.24 This can result in several kinds of cell damage, leading to a loss of function and integrity
