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The activity of caspase-3 was assessed using a Caspase-3 Colorimetric Assay kit (Caspase-3 Assay Kit, Abcam, ab39401), which is based on the spectrophotometric detection of the color reporter molecule p-nitroaniline (pNA) following cleavage from the labeled substrate DEVD-pNA (caspase-3) as an index

Cardiovascular System -- General Support

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Early clinical trials in LRRK2 asymptomatic carriers can be a consideration