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[DOI] [PubMed] [Google Scholar] 197.Alaee S, Mirani M, Derakhshan Z, Koohpeyma F, Bakhtari A

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Senomorphics: Modulating the Senescence-Associated Secretory Phenotype (SASP) Unlike senolytic therapies that aim to directly eliminate senescent cells, senomorphics work by modulating the senescence-associated secretory phenotype (SASP), which consists of pro-inflammatory cytokines, chemokines, growth factors, and extracellular matrix-degrading enzymes secreted by senescent cells