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Indeed, this metabolic pathway was first recognized by Otto Warburg, during his research on tumor cells, which are characterized by increased glucose uptake, high rate of glycolysis, followed by lactic acid fermentation in conjunction with a reduced level of oxidative phosphorylation (OXPHOS), even in the presence of abundant oxygen

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Astrocytes modulate extracellular neurotransmitter levels and excitatory neurotransmission in dorsolateral striatum via dopamine D2 receptor signaling