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Since exposure to PAHs and tobacco smoke can alter the cell cycle by inducing apoptosis in the testis cells (Xu et al., 2019), we explored putative changes in the whole expression of Bax and Bcl-2 as markers of apoptotic/anti-apoptotic homeostasis

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This causes ups and downs in metabolism and in the production of enzymes from the digestive tract which is the opposite of “homeostasis”