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Shao et al., 2022) which experience deteriorating oxidative balance and increasing oxidative stress, are also used to assess the beneficial effects of NAC

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Moreover, we revealed significant accumulation of metHb and oxHb within human complicated atherosclerotic lesions—covalently cross-linked globin-globin multimers, and dityrosine formation occurs upon IPH—suggesting that the above-mentioned reactions take place in such lesions (Nagy et al., 2010