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The vertebral fracture risk reduction was numerically superior to teriparatide in a head-to-head comparison arm of the same trial, though the study was not specifically powered for that comparison

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In case the participant had not reached at least the first sleep stage 30 min after the administration of the first drug, the second drug was chosen: the participants who received Dex as the first drug received Mel as the second drug, and those who received Mel as the first drug were given Dex (route of administration was again randomly chosen)