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Therefore, most physicians will refuse to administer repeated cortisone injections into the same joint over a short period of time, simply because too much cortisone may cause more harm than good

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The specific effects and mechanisms involved are as follows: 1) alleviates ovarian oxidative injury, increases the levels of Nrf2, heme oxygenase-1(HO-1), SOD, and SOD1 while reducing ROS production and MDA levels