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43,44 In the absence of cesR, Lm becomes less virulent in mice upon intragastric infection, but not after intraperitoneal inoculation, thus suggesting a prime role for CesRK TCS in Lm pathogenicity
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As a principle, the concept established the rat model of the direct cell lesion (necrosis) and the direct defensive immediate response (cytoprotection) [41,42,43,44,45,46,47,48,49]