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The pH in GBM tumors is drastically lower than that of normal tissues, which enables the acid-sensitive molecules in the polymer to break the micelles responsively so that the nano delivery system burst to release the drugs carried in tumor cells in a controllable manner [188,189]

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doi: 10.1002/acn3.54 200 LiQHanXLanXGaoYWanJDurhamFet al