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According to the results from in vitro and in vivo studies, tanshinone IIA pretreatment protects the liver from APAP-induced liver injury by activating Nrf2 and increasing the mRNA and protein levels of the Nrf2 target genes glutamate-cysteine ligase catalytic subunit (GCLC), NQO1, and HO-1 (Wang et al., 2016)
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Thymosin beta-4 is a 43-amino-acid polypeptide found in nearly every cell, with its highest concentrations in platelets, white blood cells, plasma, and wound fluid
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